During sexual arousal, nerves release chemicals that increase blood flow into the penis. Blood flows into two erection chambers in the penis, made of spongy muscle tissue (the corpus cavernosum).
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Erectile dysfunction is defined as the inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse. It is estimated to affect 20 to 30 million men in the US. ED may result from impairment of one or most commonly, a combination of factors: psychological, neurologic, hormonal, arterial, and venous. More recently it has become clear that, in many cases, ED may be a "silent marker" for the later development of endothelial dysfunction and eventually, cardiovascular disease.
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