Can we state Tapentadol equally as strong opioid & strong analgesic?



  • Tapentadol is an opioid analgesic that’s consumed orally to relieve moderate to severe pain. Just like Tramadol, it has a dual mechanism of actions - as a µ-opioid receptor agonist and via reuptake of norepinephrine.

    However, its use for pain relief has brought us questions with equally surprising answers. Both analgesics and opioids relieve pain but an analgesic does so by helping the patient achieve analgesia, a state in which there’s an inability to feel any pain. Opioids, on the other hand, either temporarily affect or completely eliminate any sensation.

    Interestingly, Tapentadol achieves both these results which is why it’s called an opioid analgesic. That’s why the bigger question is not whether it’s an analgesic or an opioid but whether it’s more of an analgesic or more of an opioid.

    What do experts say?

    According to a experts closely observed the activity of Tapentadol in various cases under multiple scenarios and all the results point in the same direction.

    Unlike mono-mechanistic opioids, the μ-load of tapentadol can be less than 100%. The study found it to be somewhere between 34-40% as per the trials. On the other hand, the significant contribution of tapentadol’s analgesic action in relieving pain clearly underlines that it’s more of an analgesic than an opioid.

    Interestingly, a drug need not be a strong opioid to be a strong analgesic and that’s the case with Tapentadol as it’s an highly effective analgesic with a weak opioid component.

    Where does that place Tapentadol?

    Since analgesics are basically painkillers, Tapentadol does not necessarily require prescription and can be consumed for pain management. Moreover, this lets consumers or buyers buy Tapentadol without prescription.

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